American Cruise Lines is the only major river cruise line sailing exclusively U.S. waterways — under the American flag, with American crews, on the rivers that shaped this nation. From the legendary Mississippi to the Columbia-Snake, the Hudson, and the historic rivers of New England, American Cruise Lines delivers an intimate small-ship experience for up to 190 guests. Browse 2026–2028 sailings at guaranteed lowest prices, or call a specialist at 1-800-528-9300.
Questions before you book? American Cruise Lines FAQs → — cabins, what’s included, excursions & how the Pavlus discount works.
| Nights | Cruise | Departure | Ship | American Cruise Lines Price | Pavlus Discounted Price |
|---|---|---|---|---|---|
| 7 | New England & East Coast | Oct 23 – Oct 30, 2026 | American Independence | American Cruise Lines Price $4,925 per person, double occupancy · Standard Waterview | Get Our Discounted Price → |
| 7 | Mississippi River | Oct 23 – Oct 30, 2026 | American Serenade | American Cruise Lines Price $5,275 per person, double occupancy · Standard Balcony | Get Our Discounted Price → |
| 7 | Hudson River | Oct 23 – Oct 30, 2026 | American Legend | American Cruise Lines Price $8,395 per person, double occupancy · Premium Balcony | Get Our Discounted Price → |
| 5 | Columbia & Snake Rivers | Oct 24 – Oct 29, 2026 | American West | American Cruise Lines Price $4,125 per person, double occupancy · Standard Waterview | Get Our Discounted Price → |
| 7 | Columbia & Snake Rivers | Oct 24 – Oct 31, 2026 | American Harmony | American Cruise Lines Price $6,695 per person, double occupancy · Standard Balcony | Get Our Discounted Price → |
| 7 | Columbia & Snake Rivers | Oct 24 – Oct 31, 2026 | American Jazz | American Cruise Lines Price $6,695 per person, double occupancy · Standard Balcony | Get Our Discounted Price → |
| 7 | Hudson River | Oct 24 – Oct 31, 2026 | American Ranger | American Cruise Lines Price $8,395 per person, double occupancy · Premium Balcony | Get Our Discounted Price → |
| 7 | Puget Sound & Northwest | Oct 25 – Nov 1, 2026 | American Constitution | American Cruise Lines Price $5,325 per person, double occupancy · Deluxe Waterview | Get Our Discounted Price → |
| 7 | Mississippi River | Oct 26 – Nov 2, 2026 | American Heritage | American Cruise Lines Price $4,925 per person, double occupancy · Standard Waterview | Get Our Discounted Price → |
| 7 | Columbia & Snake Rivers | Oct 26 – Nov 2, 2026 | American Pride | American Cruise Lines Price $5,470 per person, double occupancy · Standard Waterview | Get Our Discounted Price → |
| 7 | Hudson River | Oct 26 – Nov 2, 2026 | American Glory | American Cruise Lines Price $6,690 per person, double occupancy · Premium Waterview | Get Our Discounted Price → |
| 7 | New England & East Coast | Oct 27 – Nov 3, 2026 | American Star | American Cruise Lines Price $4,425 per person, double occupancy · Standard Waterview | Get Our Discounted Price → |
| 7 | Puget Sound & Northwest | Oct 27 – Nov 3, 2026 | American Constellation | American Cruise Lines Price $5,325 per person, double occupancy · Deluxe Waterview | Get Our Discounted Price → |
| 10 | New England & East Coast | Oct 27 – Nov 6, 2026 | American Pioneer | American Cruise Lines Price $8,845 per person, double occupancy · Premium Balcony | Get Our Discounted Price → |
| 14 | Southeast & Florida | Oct 27 – Nov 10, 2026 | American Liberty | American Cruise Lines Price $10,970 per person, double occupancy · Premium Balcony | Get Our Discounted Price → |
| 7 | Mississippi River | Oct 28 – Nov 4, 2026 | American Splendor | American Cruise Lines Price $4,925 per person, double occupancy · Standard Waterview | Get Our Discounted Price → |
| 7 | Mississippi River | Oct 28 – Nov 4, 2026 | American Symphony | American Cruise Lines Price $5,635 per person, double occupancy · Standard Balcony | Get Our Discounted Price → |
| 7 | Columbia & Snake Rivers | Oct 28 – Nov 4, 2026 | American Song | American Cruise Lines Price $6,360 per person, double occupancy · Standard Balcony 2 | Get Our Discounted Price → |
| 7 | Columbia & Snake Rivers | Oct 28 – Nov 4, 2026 | American Encore | American Cruise Lines Price $7,420 per person, double occupancy · Deluxe Balcony | Get Our Discounted Price → |
| 7 | Southeast & Florida | Oct 30 – Nov 6, 2026 | American Independence | American Cruise Lines Price $4,425 per person, double occupancy · Standard Waterview | Get Our Discounted Price → |
Prices listed are subject to change, based on availability, and are per person based on double occupancy. Instant Savings is either in the form of a discount, Pavlus Cash Back sent closer to Departure, or Onboard Credit depending on the cruise line.
American Cruise Lines offers an experience found nowhere else: America’s rivers, American ships, American crews. Pavlus gets you the best price.
Our high-volume partnership with American Cruise Lines means exclusive savings unavailable when booking direct or through other agencies.
Our advisors have personally sailed with American Cruise Lines. We match you to the right itinerary for your travel style and budget.
Find the same sailing cheaper anywhere? We’ll match it — and often add a Pavlus exclusive amenity on top.
No service fees, no booking fees — ever. Every dollar you spend goes toward your river cruise experience.
*Cash back is calculated on the net fare, which is the fare remaining after travel agency commission is deducted, not on the total booking price. Cash back will therefore be less than 10% of your total. See full terms here.