American Cruise Lines is the only major river cruise line sailing exclusively U.S. waterways — under the American flag, with American crews, on the rivers that shaped this nation. From the legendary Mississippi to the Columbia-Snake, the Hudson, and the historic rivers of New England, American Cruise Lines delivers an intimate small-ship experience for up to 190 guests. Browse 2026–2028 sailings at guaranteed lowest prices, or call a specialist at 1-800-528-9300.
Questions before you book? American Cruise Lines FAQs → — cabins, what’s included, excursions & how the Pavlus discount works.
| Nights | Cruise | Departure | Ship | American Cruise Lines Price | Pavlus Discounted Price |
|---|---|---|---|---|---|
| 7 | New England & East Coast | Nov 12 – Nov 19, 2026 | American Ranger | American Cruise Lines Price $6,075 per person, double occupancy · Premium Balcony | Get Our Discounted Price → |
| 6 | Mississippi River | Nov 14 – Nov 20, 2026 | American Heritage | American Cruise Lines Price $3,630 per person, double occupancy · Standard Waterview | Get Our Discounted Price → |
| 7 | Mississippi River | Nov 14 – Nov 21, 2026 | American Melody | American Cruise Lines Price $5,275 per person, double occupancy · Standard Balcony | Get Our Discounted Price → |
| 7 | Southeast & Florida | Nov 14 – Nov 21, 2026 | American Pioneer | American Cruise Lines Price $6,575 per person, double occupancy · Premium Balcony | Get Our Discounted Price → |
| 7 | Southeast & Florida | Nov 15 – Nov 22, 2026 | American Eagle | American Cruise Lines Price $5,990 per person, double occupancy · Premium Waterview | Get Our Discounted Price → |
| 7 | Southeast & Florida | Nov 15 – Nov 22, 2026 | American Legend | American Cruise Lines Price $6,995 per person, double occupancy · Premium Balcony | Get Our Discounted Price → |
| 7 | Mississippi River | Nov 16 – Nov 23, 2026 | American Serenade | American Cruise Lines Price $5,275 per person, double occupancy · Standard Balcony | Get Our Discounted Price → |
| 6 | Southeast & Florida | Nov 17 – Nov 23, 2026 | American Symphony | American Cruise Lines Price $4,065 per person, double occupancy · Standard Balcony | Get Our Discounted Price → |
| 7 | Southeast & Florida | Nov 17 – Nov 24, 2026 | American Liberty | American Cruise Lines Price $6,495 per person, double occupancy · Premium Balcony | Get Our Discounted Price → |
| 7 | Southeast & Florida | Nov 18 – Nov 25, 2026 | American Glory | American Cruise Lines Price $5,490 per person, double occupancy · Premium Waterview | Get Our Discounted Price → |
| 7 | Southeast & Florida | Nov 18 – Nov 25, 2026 | American Maverick | American Cruise Lines Price $6,075 per person, double occupancy · Premium Balcony | Get Our Discounted Price → |
| 6 | Mississippi River | Nov 20 – Nov 26, 2026 | American Heritage | American Cruise Lines Price $3,230 per person, double occupancy · Standard Waterview | Get Our Discounted Price → |
| 7 | Mississippi River | Nov 21 – Nov 28, 2026 | American Melody | American Cruise Lines Price $5,275 per person, double occupancy · Standard Balcony | Get Our Discounted Price → |
| 7 | Southeast & Florida | Nov 21 – Nov 28, 2026 | American Pioneer | American Cruise Lines Price $6,075 per person, double occupancy · Premium Balcony | Get Our Discounted Price → |
| 7 | Southeast & Florida | Nov 22 – Nov 29, 2026 | American Eagle | American Cruise Lines Price $5,130 per person, double occupancy · Premium Waterview | Get Our Discounted Price → |
| 7 | Southeast & Florida | Nov 22 – Nov 29, 2026 | American Legend | American Cruise Lines Price $6,495 per person, double occupancy · Premium Balcony | Get Our Discounted Price → |
| 14 | Southeast & Florida | Nov 23 – Dec 7, 2026 | American Ranger | American Cruise Lines Price $11,860 per person, double occupancy · Premium Balcony | Get Our Discounted Price → |
| 7 | Southeast & Florida | Nov 24 – Dec 1, 2026 | American Liberty | American Cruise Lines Price $6,495 per person, double occupancy · Premium Balcony | Get Our Discounted Price → |
| 7 | Southeast & Florida | Nov 25 – Dec 2, 2026 | American Glory | American Cruise Lines Price $5,490 per person, double occupancy · Premium Waterview | Get Our Discounted Price → |
| 7 | Southeast & Florida | Nov 25 – Dec 2, 2026 | American Maverick | American Cruise Lines Price $6,075 per person, double occupancy · Premium Balcony | Get Our Discounted Price → |
Prices listed are subject to change, based on availability, and are per person based on double occupancy. Instant Savings is either in the form of a discount, Pavlus Cash Back sent closer to Departure, or Onboard Credit depending on the cruise line.
American Cruise Lines offers an experience found nowhere else: America’s rivers, American ships, American crews. Pavlus gets you the best price.
Our high-volume partnership with American Cruise Lines means exclusive savings unavailable when booking direct or through other agencies.
Our advisors have personally sailed with American Cruise Lines. We match you to the right itinerary for your travel style and budget.
Find the same sailing cheaper anywhere? We’ll match it — and often add a Pavlus exclusive amenity on top.
No service fees, no booking fees — ever. Every dollar you spend goes toward your river cruise experience.
*Cash back is calculated on the net fare, which is the fare remaining after travel agency commission is deducted, not on the total booking price. Cash back will therefore be less than 10% of your total. See full terms here.